Mitochondrial Dysfunction Mediates Aldosterone-Induced Podocyte Damage
نویسندگان
چکیده
منابع مشابه
Mitochondrial dysfunction is an early event in aldosterone-induced podocyte injury.
We previously showed that mitochondrial dysfunction (MtD) is involved in an aldosterone (Aldo)-induced podocyte injury. Here, the potential role of MtD in the initiation of podocyte damage was investigated. We detected the dynamic changes of urinary protein, urinary F2-isoprostane and renal malondialdehyde levels, kidney ultrastructure morphology, mitochondrial DNA (mtDNA) copy number, mitochon...
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ژورنال
عنوان ژورنال: The American Journal of Pathology
سال: 2011
ISSN: 0002-9440
DOI: 10.1016/j.ajpath.2011.01.029